Strong Evidence Links Soft Drink Consumption To Obesity, Diabetes

The case against swigging soda just got stronger. A large systematic review reveals clear associations between consumption of nondiet soft drinks and increased calorie intake and body weight.

Full-calorie soft drinks are also linked with reduced intake of milk and fruit and increased risk of type 2 diabetes. "Recommendations to reduce population soft drink consumption are strongly supported by the available science," concludes the review of 88 studies.

The American Beverage Association, however, presents a different view on its Web site. "It is not feasible to blame any one food product or beverage as being a sole contributor to obesity …. No science supports such a claim."

Carbonated soft drinks are the single largest source of calories in the American diet, according to a 2005 report called "Liquid Candy," produced by the nonprofit Center for Science in the Public Interest (CSPI).

In Obesity, Brain Becomes 'Unaware' Of Fat

Critical portions of the brain in those who are obese don't really know they are overweight, researchers have reported in the March issue of the journal Cell Metabolism, published by Cell Press. These findings in obese mice show that a sensor in the brain that normally detects a critical fat hormone - causing a cascade of events that keeps energy balance in check - fails to engage. Meanwhile, the rest of the metabolic pathway remains ready to respond.

"Obesity is not a failure of will power, it is a biological failure," said Michael Cowley of Oregon Health & Science University of his group's findings in the mice. "The brain is not aware that the body is obese."

If the same is true in humans, he added, people may be consciously aware that they are overweight, but "that's different from the homeostatic circuitry being aware."

The new results also bolster evidence that a suppressor called SOCS-3 may be responsible for the loss of sensitivity to the fat hormone known as leptin.