Obesity Causes Breakdown In System Which Regulates Appetite And Weight

New research led by scientists at the Oregon National Primate Research Center demonstrates how obesity causes the breakdown of a brain system that regulates appetite. The research provides a clear picture of some factors involved in obesity. More than 60 percent of American adults are overweight and more than 30 percent are obese The study results may have also identified possible targets for new drug therapies aimed at assisting individuals in weight loss. The research is published in the March issue of Cell Metabolism. The research provides new understanding of leptin resistance. Leptin is a hormone secreted by fat cells. It can suppress food intake by affecting brain cells that control appetite. However, high levels of leptin which can be found in severely overweight individuals, can lead to leptin resistance.